Prep the injection. Progesterone shots and pain stjoegal I am 5 wks pregnant after an FET. Hello, Curious if anyone has ever experienced lower back pain and stiffness as well as hip joint aches and stiffness from the progesterone injections? Most people recommend injecting fast and steady. He did the draw back to make sure that there was no blood, but it's painful to even sit in a chair, let alone try to walk. Took hot shower just before the injection, especially let the hot water rain for around a minute on my back. The different oils used in the injections differ in amount of pain caused. When water is very hot put a washcloth under the water, squeeze out excess water, then wrap the washcloth tightly around the medicine in the syringe for about 3-5 minutes. ShotBlocker. I can't use a warm compress and can only take some Tylenol. Pierce the rubber stopper of the progesterone vial. It helps prepare your body for conception and pregnancy and regulates the monthly . *Allow area to dry before injecting Change needle, and insert needle at a 90 degree angle. Progesterone can cause cramping for various reasons. Step Two: Warm the Injection Medication. DESCRIPTION . I have a pain that radiates from my butt all the way down my leg. 4 Your injection should not go into one of these bumps and it should be at least an inch away from a knot to avoid pain and to help the absorption of progesterone. . I have been on oral compounded progesterone for about 5 years. Before administering the progesterone shots, put the vial in a glass of very warm water. Progesterone occurs as a white or creamy white, crystalline powder or colourless crystals. Shorter, thinner, nonvisible needle. pain, irritation, and/or redness at the injection area; skin sensitivity reactions consisting of . These oils are typically used the least. PROGESTERONE INJECTION USP IN SESAME OIL FOR INTRAMUSCULAR USE ONLY Rx only PIN221-WAT/2 Revised: August 2018 . Progesterone injection, a progestin, is a sterile solution of progesterone in a suitable vegetable oil available for . It is also available in the form of vaginal or rectal suppositories, vaginal gels, oil solutions for intramuscular . Progesterone does other important tasks during pregnancy, including: helping to . If I sit afterwards it hurts worse. The Makena you know — ready to go. You shouldn't be icing AFTER though -- heat or movement is better to get the oil absorbed. Cottonseed oil is less likely to cause injection site pain. Or maybe you hate every single needle. 4 comments 100% Upvoted I can't use a warm compress and can only take some Tylenol. It plays this important role until the placenta is formed around week 10 and establishes its own blood supply. It occurs in approximately 20% of women at ovulation only and in no way is it dangerous. The shot itself is not a big deal so that is not my problem. Perhaps regular shots don't bother you. Pain when passing urine. It also is helpful if I can watch the needle go in.that's probably weird, but I don't tense. Intramuscular (IM) injections of progesterone in oil (PIO) and vaginal administration of progesterone are the primary routes of administration. I'm just now starting to experience some side effects from the progesterone. August 2011. in Infertility. After about 30-60 seconds apply hot water bottle, or heating pad, and massage area vigorously with the flattened bottle as an "in between" layer for at least two minutes. 1. It's rare, but some people may have a mild allergic reaction to the oil component. After natural ovulation, the follicle that contained your egg turns into the corpus luteum. 4. If this occurs, cottonseed, olive, or ethyl oleate oils are used instead. Gaining or losing weight - rare. Those taking extra doses of this hormone because of a deficiency, or for any other reason may also find that cramping is a common side effect, whether due . Vaginal dryness - rare. As injectible progesterone is very viscous, you need to use a thicker syringe to inject it, which can be painful at times, but the suppositories are easy to use and can be gently . • Adverse effects: Local vaginal reactions such as irritation or itching from suppositories. Allergic reaction is possible to sesame and peanut oil. 2. Pain at the injection site is common. The RE then had me try progesterone in sesame oil injection. DO NOT apply ice to your hips before giving progesterone shots. 4. Administered in the back of the upper arm—no need for patients to disrobe. Keep warm compress on for some time. Seizures . Obviously, I still have to take my meds. Administered in ~15 seconds. In order to help minimize any pain or discomfort, the following tricks and tips are often recommended: • Apply ice to the injection site 30 to 60 seconds before to help numb the area. I don't think lidocaine would help. The intramuscular injection of progesterone is in oil form. Any ideas on how to deal with the pain? Either way, the progesterone in oil shot experience is frankly unlike your other IVF medications. It is a progestogen and is used in combination with estrogens mainly in hormone therapy for menopausal symptoms and low sex hormone levels in women. The same is true for IM injections, but sometimes it's actually better to use heat for ten minutes before and after the medication. The good news is that the overwhelming majority of scientific . I've had my transfer and am waiting for the results. SIDE EFFECTS: Pain /swelling at injection site, breast tenderness, headache, weight gain /loss, acne, nausea, increased body/facial hair, loss of scalp hair, drowsiness, or dizziness may occur. The heat helps to spread out the oil because it can "clump" and cause painful knots. Ethyl oleate is the thinnest oil available. After all of the medication is injected the needle gets pulled out, and I hold pressure on the poke mark for a couple minutes to stop the minor bleeding and bit of oil oozing out. Hold the syringe in your hand with pressure on the . On the other hand, progesterone suppository may cause lower serum levels which may result in poor implantation; however, numerous clinical trials in this field have had paradoxical results [19-21]. So I was then put on compounded suppositories which looked like white bullets. Research to find a patient-compliant and . I don't recall any specific injection that was painful or felt different, but I think I might have hit something because it's a different type of pain than regular soreness and hasn't gone away. It is frequently produced with sesame oil, which some people are sensitive to. Injecting yourself in the behind can be a tough contortion on your own. It is not a cyst rupturing, but the follicle containing a mature egg bursting to release the egg. 3. But IVF isn't natural. I have always thought I have a high tolerance for pain but this poi is bringing me to my knees. 5. It is also used in women to support pregnancy and fertility and to treat gynecological disorders. The worst of the worst. I am on progesterone suppositories and shots (in sesame seed oil) until 9/9. Progesterone is available in both sesame oil and even in ethyl oleate. Meanwhile had the heating pad ready and warm 3. Requill shares her PIO shot tips for a pain free injection during her. If so, you can use an ice pack post-injection to minimize bruising and swelling. Allergic reaction is possible to sesame and peanut oil. I have always thought I have a high tolerance for pain but this poi is bringing me to my knees. It is thinner than peanut oil, and less likely to cause an allergic reaction. The best thing to do is ice before. Progesterone Oil Injection Pain I've had my transfer and am waiting for the results. Peanut and Cottonseed Oils. Flushing. Progesterone (P4) is a medication and naturally occurring steroid hormone. Progesterone injections come in an oil base that can be given to you at your physician's office, at an outpatient clinic or in the hospital. Although intramuscular progesterone is not approved by the US Food and Drug Administration for use in IVF, some physicians still prefer giving progesterone in this traditional form because it produces higher progesterone levels in the blood than other administration methods. Tuck the PIO vial into the front of my bra so the oil can reach body temperature. • Wait until alcohol on skin has evaporated. It is also helpful for women with absent menstrual periods or abnormal menstrual . I'm on day 34 of progesterone shots. Pain during and post injection is likely; Important to note: 2 needles are NOT necessary for this injection. Lidocaine's not necessarily going to fix that. If you feel pain while the injection is in progress, try injecting slower. Sesame oil is the most common oil used in progesterone injections. I put the bottle in my bra for 5 minutes before my husband injects me. Obviously, I still have to take my meds. Brush my teeth. It's only on the one side. Perineal pain. If you are very thin, insert needle so that ¼ to ½ inch is left outside of body. . The different oils used in the injections differ in amount of pain caused. If you are still ovulating, then the pain is called Mittelschmerz, see here, here and here. We had been switching needles as the instruction video showed (1 for mixing, 1 for injection) but recently realized that using only the 22g is preferred by our clinic (oops). Tell your doctor if you have swelling, weight gain, or trouble breathing. Progesterone Oil Injection Pain. Turn on my heating pad and put it on my bed. This is especially true for progesterone because of the thick oil you have to inject. For patients on progesterone in oil, local pain and redness at injection sites is common. Could the oil have tricked down the muscle somehow? I've always assumed the pain is from the density of the oil being shoved into the muscle. . Your FSH injections produce multiple follicles. If this occurs, cottonseed, olive, or ethyl oleate oils are used instead. . Passing urine more often. . 1. Progesterone does other important tasks during pregnancy, including: helping to . We had been switching needles as the instruction video showed (1 for mixing, 1 for injection) but recently realized that using only the 22g is preferred by our clinic (oops). -breathing problems. In the rare cases that conttonseed oil causes an allergic reaction, olive oil or ethyl oleate is used. Progesterone in oil is, well, in oil. As part of your IVF (In Vitro Fertilization) program, your doctor may prescribe progesterone in oil for fertility. Progesterone in oil, because it is an intramuscular injection, can cause redness, swelling, pain, and lumps at the site of the injection. Most side effects of progesterone injections are mild and temporary. Progesterone in oil injections are given to women undergoing in-vitro fertilization. Allergic reactions can occur with sesame oil, and in that instance the patient will often be switched to progesterone in a different oil base, typically ethyl oleate. Laid on the bed sideways with the decided injection side facing up and put the heating pad especially on the decided site for the . Progesterone, along with altrenogest, which is a synthetic progestin, is used extensively in the reproductive management of mares to control the reproductive cycle, help maintain pregnancy, and help with behavior modification. Anonymous. Subject: Re:muscle soreness / pain after progesterone oil injection. It is odorless and is stable in air. This medicine may cause you to swell or keep fluid in your body. Intramuscular progesterone (Gestone) versus vaginal progesterone suppository (Cyclogest) for luteal phase support in cycles of in vitro fertilization-embryo transfer: patient preference and drug efficacy . These caused burning and bleeding. This type of intramuscular (IM) injection is used to help thicken your uterine lining to protect the embryo and secure its healthy growth and development. Progesterone and back pain. Nausea - rare. Progesterone in oil (sesame, peanut or olive) syringes: 3 . Any ideas on how to deal with the pain? Or, if hot water is not available, just roll the vial between your hands for a few minutes to warm the oil. Progesterone is one of the hormones in our bodies that stimulates and regulates various functions. It is soluble in alcohol, in acetone, and in dioxane; sparingly soluble in vegetable oils; practically insoluble in . . Many of our surrogates tell us that sesame oil results in some of the most manageable injection site tenderness. The other forms of progesterone ( Prometrium, Crinone, and Endometrin) can cause vaginal discharge and irritation. Ethyl oleate is the thinnest oil available. Some of the most common side effects include: Pain or swelling at the injection site - common. This is the trigger for progesterone, which makes your womb lining super-ready for the fertilised embryo. I've been having hip pain for about 3 weeks after doing progesterone injections. Anyone else experience this? Progesterone injection, USP, a progestin, is a sterile solution of progesterone in a suitable vegetable oil available for intramuscular use. (Heat and massage will break up progesterone and decrease pain). Definitely not after, though, because then it makes the oil clump up and not disperse. Which means it's thick, and needs to be injected slowly. #pioshot #pioinjection #ivfinjectionLearn how to do a pain free progesterone injection. Depression or other mood changes. This makes it harder to tense up the buttock/hip area you are giving the shot to. 2. Hold the syringe in your hand with pressure on the . If anything it's getting worse. When progesterone is manufactured as a liquid for intramuscular injections, it is mixed with an oil. The different oils used in the injections differ in amount of pain caused. Severe local skin reactions to progesterone in oil are fairly rare. Get a shower. In the past I have taken 100 mg at night. Withdraw needle quickly and immediately massage injection site. Oral route (Capsule, Liquid Filled) Estrogens plus progestin therapy should not be used for the prevention of cardiovascular disease or dementia.Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) have been reported with estrogen plus progestin therapy. Please check with your doctors before trying this.. Practically insoluble in water, it is soluble in alcohol, acetone, and dioxane and sparingly soluble . Peanut and Cottonseed Oils. Or if standing, have them put the "shot . Good luck to your friend. The hormone is produced in the ovaries, the placenta (when a woman gets pregnant) and the adrenal glands. Turn your foot to the inside- less likely to tense your muscles. To help you remember, use it at the same time each day.Tell your doctor if your condition persists or worsens. Here is a trick I figured out during my last IVF pregnancy to make PIO or any injection nearly painless. Injection of progesterone produces the highest blood levels. PROGESTERONE INJECTION USP IN SESAME OIL FOR INTRAMUSCULAR USE ONLY Rx only DESCRIPTION Progesterone injection, a progestin, is a sterile solution of progesterone in a suitable vegetable oil available for intramuscular use. With an injection, you just need to take it once a day, usually at night, to fulfill your daily requirement whereas the suppositories need to be taken 3-4 times a day. Pressure and Massage Here is a simple thing you can do w/o changing a thing about injection technique: have patient either lie sideways (laterally) and put the "shot" leg forward, knee bent, resting in infront of the other leg. -breast tissue changes or discharge. Cottonseed oil is less likely to cause injection site pain. I just had my FET 2 days ago and have been on the injections for the last 7 days. Possible side effects of any form of progesterone include drowsiness, fluid retention, increased breast tenderness, nausea, increased irritability, diarrhea or depression. Open a new alcohol pad, and swab the injection area (see image). There can be breast tenderness, pain or swelling at the site of injection, weight gain, weight loss, headache, and . This will help numb the area and minimize pain associated with injection. breast pain inflammation or infection of the vagina visible water retention weight gain weight loss changes in appetite headache reactions at the site of the injection generalized weakness intense. Some people can be trained to give their own progesterone injections at home. When water is very hot put a washcloth under the water, squeeze out excess water, then wrap the washcloth tightly around the medicine in the syringe for about 3-5 minutes. Withdraw the dosage ordered. For like, thirty minutes. Please check with your doctors before trying this.. Progesterone can also cause a localized reaction, with hard lumps, redness or itching around the injection site. Warning. This helps thin the oil and allows for smoother injections. Jewls819 07/06/19 Hi there, I'm on day 22 of progesterone shots (5 weeks pregnant) and have been feeling pain on my bum (which is normal)but have also recently feeling numbness and pain on the side of the upper right leg. Here are our tips: Get an injection buddy Ask your partner or a friend to help you out. Progesterone in Oil pain 41epoH Jan 18, 2017 • 3:03 PM Hi all, I have been doing my progesterone in oil shots for only 4 days so far and the pain is unbearable. My nurse advised Tylenol and ice or heat. It is thinner than peanut oil, and less likely to cause an allergic reaction. Progesterone Injection USP, a progestin, is a sterile solution of progesterone in a suitable vegetable oil available for intramuscular use. The reason IVF patients need extra progesterone is purely chemical. Of all the tortures infertility brings - estrogen patches, clomid, metformin, twice daily stim injections, ultrasounds upon ultrasounds, daily blood draws - progesterone in oil is the ultimate torturer. 2. It plays this important role until the placenta is formed around week 10 and establishes its own blood supply. Has anyone found a remedy that works well to reduce the pain? These oils are typically used the least. The shot itself is not a big deal so that is not my problem. Walk it off! 3. Inject 1cc of air into the vial. E. After the injection: 1. Open. Women with normal amounts of this hormone in their bodies may experience cramps during menstruation, which is brought on by progesterone. The most common side effect of progesterone in oil is an injection site reaction, such as pain or swelling. • Make certain that air bubbles are removed from the syringe before injecting. Progesterone Injections - Numbness and Pain? After 5 days, I developed severe redness, swelling and pain. Progesterone can be taken by mouth, in through the vagina, and by . It is also . I get 1 ml of Progesterone in Ethyl Oleate every night, and tonight after my husband did it, I couldn't put any weight on my leg! Designed for ease of use, the FDA‑approved Makena subcutaneous auto‑injector is: Pre‑filled auto-injector that is ready to use out of the box. Memory problems or loss. . Progesterone plays a role in maintaining pregnancy. I have had really bad PMS and sleeping problems lately (I am 45 1/2) and so I decided, after some research, to increase my dose to 200 mg and I am also using some health food store progesterone cream in the AM. . Turn the vial upside down, making sure the tip of the needle is below the fluid level. Well, yes, you're injecting something into your muscle, so it's not surprising that it would be sore. pain, irritation, and/or redness at the injection area; skin sensitivity reactions consisting of urticaria, pruritus . The Bastard-King Joffrey. There are three other oil available to use in progesterone injections if the patient is allergic to both sesame and peanut oils. You'll find you won't need as much progesterone. Step Two: Warm the Injection Medication. My butt muscles have gotten so sore from the injections. Run super hot water in your sink to heat the PIO shot to your body temperature. Some people recommend not icing before either. Many of our surrogates tell us that sesame oil results in some of the most manageable injection site tenderness. Get dressed in my undergarments. Progesterone in oil (sesame, peanut or olive) syringes: 3 . What is Progesterone in Oil and How Does It Work? . For days after each progesterone oil injection, I have pretty serious injection spot pain. Cottonseed oil is also a thinner compound and it is said to cause less pain at the site of the injection but because it hasn't been tested a lot it isn't normally used so make sure that you keep that in mind when the time does come for you to get started. Fast or abnormal heartbeat. Here is a trick I figured out during my last IVF pregnancy to make PIO or any injection nearly painless. Wash my hands. These . Raise your hand if you've been personally victimized by a progesterone in oil injection: Um, YES. Natural progesterone is dissolved in an oil for injection. Run super hot water in your sink to heat the PIO shot to your body temperature. For days after each progesterone oil injection, I have pretty serious injection spot pain. However availability of IM P has been problematic since it is only available in few countries and injections are considered painful to . Progesterone in Oil pain 41epoH Jan 18, 2017 • 3:03 PM Hi all, I have been doing my progesterone in oil shots for only 4 days so far and the pain is unbearable. Pain during and post injection is likely; Important to note: 2 needles are NOT necessary for this injection. 1. How do you make progesterone in oil less painful? This report describes the administration preferences expressed by women with infertility that were given progesterone vaginal insert (PVI) or progesterone in oil injections (PIO) for luteal phase . Sometimes progesterone in oil can accumulate in your muscle, causing little knots or bumps, known as panniculitis. Sesame oil is the most common oil used in progesterone injections. Allergic reactions can occur with sesame oil, and in that instance the patient will often be switched to progesterone in a different oil base, typically ethyl oleate. If you're suffering through IVF, do yourself a favor: buy these three things and have a (slightly) easier cycle. Intramuscular oil-based injections are obviously painful and have side effects like abscess formation. Warm up the vial Warm up the vial a bit in the crease of your elbow or by rolling the vial back and forth in your hands. Using the 3cc syringe with a 1.5 inch needle, pull back on the plunger to the 1cc mark. Oct 21, 2002. . (This helps decrease lumps and pain.) -changes in vaginal bleeding during your period or between your periods. 2nd cycle: I was put on compounded progesterone capsules. If no blood shows up in the syringe it's injection time. It is also used to treat abnormal bleeding from the uterus that is due to low hormone levels and not other causes (such as fibroids, cancer of the uterus).Progesterone must not be used to test for. Dizziness - rare. If these symptoms are severe or persistent, you should talk . Allergic reaction is possible to sesame and peanut oil. With that said, you might experience some minor pain, bruising, swelling, or bleeding at the injection site. Progesterone occurs as a white or creamy white, crystalline powder. The pharmacokinetics of progesterone are dependent on its route of administration.The medication is approved in the form of oil-filled capsules containing micronized progesterone for oral administration, termed "oral micronized progesterone" ("OMP") or simply "oral progesterone". There are three other oil available to use in progesterone injections if the patient is allergic to both sesame and peanut oils. Drowsiness - rare. In the rare cases that conttonseed oil causes an allergic reaction, olive oil or ethyl oleate is used. Crinone 8% is contraindicated in patients with active thrombophlebitis or thromboembolic disorders, or a history of hormone-associated thrombophlebitis or thromboembolic disorders, missed abortion . Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. 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